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Intensive Care Medicine

Tutorial 82

Anticoagulation & Intracranial Bleeds – Management Of The Anticoagulated Patient Presenting With Intracranial Haemorrhage

Rebecca Appelboam, Exeter, UK

Email: appelboamr@doctors.org.uk

12th January 2008

Abstract

Early and aggressive reversal of INR to within the normal range with vitamin K and prothrombin complex concentrate improves outcome.

Risk of systemic embolisation in the acute phase, even in patients with mechanical heart valves, is low and temporary cessation of oral anticoagulation for 8-15 days is safe.

Risk of recurrent haemorrhage after careful reintroduction of oral anticoagulation is low.

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