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Basic Sciences

Tutorial 5

Local Anaesthetic Pharmacology

Dr Hilary Edgcombe, Dr Graham Hocking

John Radcliffe Hospital, Oxford, UK

Email: edgcombe@clara.co.uk

11/07/05

Abstract

Understanding the pharmacology of local anaesthetics enables the anaesthetist to predict the potency, speed of onset, duration of action and safety of a specific drug in a given clinical situation. This maximises the opportunity for safe and effective use of local anaesthesia in a wide variety of contexts.