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Tutorial 469

Perioperative Applications of Dexmedetomidine

Dr Gillian Crowe1†, Dr Ben Atterton2, Dr Louise Moran3
1Registrar in Anaesthesia, Connolly Hospital Blanchardstown, Dublin, Ireland
2Registrar in Anaesthesia, Rotunda Hospital, Dublin, Ireland
3Consultant Anaesthetist, Letterkenny University Hospital, Donegal, Ireland

Edited by: Dr Alex Konstantatos
†Corresponding author e-mail: gcrowe@tcd.ie

Published April 5, 2022

Abstract

Dexmedetomidine is a highly selective α2-adrenoceptor agonist. It exerts sympatholytic, analgesic, and sedative effects which make it an attractive option for the maintenance of sedation in the Intensive Care Unit (ICU) and for the conscious sedation of adults and children during diagnostic or surgical procedures. This tutorial will cover basic and practical pharmacology as well as its clinical applications in the perioperative context.