Renal Physiology – Part 2

Abstract

The proximal tubule reabsorbs 70% of the volume of glomerular filtrate (along with 70% of most of the electrolytes)
In health the proximal tubule reabsorbs 100% of the glucose from the glomerular filtrate
The long loops of Henle establish a hypertonic medullary interstitium which then allows water reabsorption from the collecting ducts of all nephrons
The variability in urine volume and concentration is dependent on what happens in the collecting ducts
For simplicity it can be considered that ADH regulates ECF osmolality and aldosterone regulates ECF volume