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Intensive Care Medicine

Tutorial 198

Rhabdomyolysis

Dr Michelle Barnard, Royal Cornwall Hospital, Truro, UK

Correspondence to michellechopra@doctors.net.uk

27TH SEPTEMBER 2010

Abstract

Rhabdomyolysis is often encountered in the intensive care setting. Patients may have few symptoms so a high level of suspicion should be maintained. Serum CK is the most sensitive indicator of muscle injury.

Initiate fluid resuscitation immediately
Treat acute hyperkalaemia
Monitor for complications including compartment syndrome
Serial CK measurement
Renal replacement therapy may be required