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  1. Virtual Library
  2. Anaesthesia Tutorial of the Week
  3. SGLT-2 Receptor Inhibitors: Pharmacology and Anaesthetic Implications

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General Topics

Tutorial 551
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SGLT-2 Receptor Inhibitors: Pharmacology and Anaesthetic Implications

Dr Merlin Watts1†, Dr Stuart McPhail2, Dr David Levy3

1Anaesthetic SHO, Torbay and South Devon NHS Foundation Trust, UK 2Anaesthetic Registrar, Torbay and South Devon NHS Foundation Trust, UK 3Anaesthetic Consultant, Torbay and South Devon NHS Foundation Trust, UK

Edited by: Dr Alex Konstantatos, ATOTW Primary Editor; Dr William Frankie Powell, ATOTW Secondary Editor.

†Corresponding author email: merlin.watts@nhs.net

DOI: 10.28923/atotw.551

 

Published July 15, 2025

Abstract

This tutorial provides an overview of the pharmacology, indications and potential complications associated with SGLT2 inhibitors. It explains perioperative considerations, focusing on the associated risk of diabetic ketoacidosis. It also compares international guidance and outlines our institution’s approach to managing these agents during surgery.

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