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Pain

Tutorial 407

Tramadol and Tapentadol: Clinical and Pharmacologic Review

John O’Connor1†, Russell Christie1, Emma Harris1, John Penning2, Jason McVicar2

1Anesthesiology Resident, The Ottawa Hospital, Ottawa, ON, Canada
2Staff Anaesthesiologist, The Ottawa Hospital, Ottawa, ON, Canada

Edited by: Amanda Baric, Visiting Anaesthetist, The Northern Hospital, Epping, VIC, Australia

Corresponding author e-mail: jooconnor@toh.ca

Published 23 July 2019

Abstract

Tramadol and tapentadol are two related molecules that are being used to treat acute pain. In this tutorial we discuss the basic pharmacology, safety and efficacy of both medications. As well, indications for use, safety recommendations and abuse potential are discussed.