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Critical Care

Tutorial 505

Levosimendan

Dr Daniel Tucker1†, Dr Diarmaid Dillon2

1Clinical Fellow in Paediatric Intensive Care, Evelina Children’s Hospital, London, UK

2Consultant Anaesthetist, Luton and Dunstable Hospital, UK

Edited by: Dr Niraj Niranjan, Consultant, Anaesthesia and Intensive Care, University Hospital of North Durham, UK

Corresponding author email: danielvtucker1986@gmail.com

Published September 12, 2023

Abstract

In this tutorial we outline the pharmacology of the novel inotrope Levosimendan, a calcium sensitizer, and we discuss the current available evidence. We also outline several other novel inotropes in development and finally we discuss the ancient ShenFu traditional Chinese medicine used in China for its beneficial inotropic properties.