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Tutorial 419

Opioid-Induced Hyperalgesia

Osmond Morris1†, Larry Crowley2

1Anaesthesia Fellow, St James’s Hospital, Dublin, Ireland

2Consultant Anaesthetist, St Vincent’s University Hospital, Dublin, Ireland

Edited by: Dr. Christopher Haley, Anaesthetic Consultant, Kingston Health Sciences, Ontario, Canada

†Corresponding author e-mail: morriso@tcd.ie

Published 3 March 2020

Abstract

Opioids are a cornerstone of anaesthetic practice. This tutorial will discuss a common opioid side effect - Opioid-induced Hyperalgesia (OIH). OIH is a phenomenon for which we have an increasing appreciation. We will discuss its proposed mechanism, clinical relevance and, lastly, evidence on its management strategies.