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Basic Sciences

Tutorial 16

Physiology of pain

Dr.K.Venugopal, Dr.M.Swamy FRCA

Darlington Memorial Hospital, UK

2nd DECEMBER 2005

Abstract

Understanding pain physiology is very important in countering it. From what is known it is clear that pain recognition involves transduction, transmission, modulation and perception. The signal is modulated at various levels before perceived. Various transmitters, facilitators and inhibitors are involved. Body responds to painful stimuli, which may be helpful or counter-productive. Better knowledge helps not only in artificial modulation of pain but also to suppress the harmful reflex responses.