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Intensive Care Medicine

Tutorial 435
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Propofol Infusion Syndrome

Monojit Paul1†

1 Anaesthesia Specialist Trainee, University Hospital of North Durham, UK

Edited by: Dr. Niraj Niranjan, Consultant, Anaesthesia and Intensive Care, University Hospital of North Durham, UK †

Corresponding author e-mail: monojitpaul@nhs.net

Published October 27, 2020

Abstract

Propofol infusion syndrome is a rare but potentially fatal condition associated with the use of propofol for longer term sedation in the critically ill patient. Prevention is the best form of management as there is no specific treatment other than the use of alternative sedation and supportive care. With propofol being one of the most widely used sedation agents in critical care, it is important that providers are aware of the prevention, diagnosis and management of this rare complication.

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