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Basic Sciences

Tutorial 428
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Vasopressin

Thomas Snell1†, Caroline Oliver2

1Anaesthetic Core Trainee, North Bristol NHS Trust, Bristol, UK

2Consultant Anaesthetist and Intensivist, North Bristol NHS Trust, Bristol, UK

Edited by: Dr. Fran Smith, Consultant Anaesthetist, North Bristol NHS Trust, Bristol, UK

†Corresponding author email: T.Snell@doctors.org.uk

Published 7 July 2020

Abstract

Vasopressin is an endogenous hormone with important roles in fluid and blood pressure homeostasis. It has a number of clinical uses because of its broad range of physiological roles including those on the cardiovascular system, fluid balance and haemostasis. Its use in catecholamine-resistant septic shock is recognised, but evidence of benefit is limited. Nevertheless, it offers a novel pharmacologic option in this cohort as it does not rely on the sympathetic nervous system to exert its effects.

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